Scientific Abstracts

Gamma knife radiosurgery is the preferred treatment for metastatic brain tumors and has proven effective for certain primary brain tumors and arteriovenous malformations.

The following published scientific papers are among those authored by experts at the University of Maryland Gamma Knife Center:

  • Dhople A, Adams J, Maggio W, Naqvi S, Regine W, Kwok Y, Long-Term Outcomes of Gamma Knife Radiosurgery for Classic Trigeminal Neuralgia: Implications of Treatment and Critical Review of the Literature, Journal of Neurosurgery, DOI: 10.3171/2009.2.JNS08977, March 2009.

  • Flannery TW, Suntharalingam M, Regine WF, Chin LS, Krasna MJ, Shehata MK, Edelman MJ, Kremer M, Patchell RA, and Kwok Y. Long-Term Survival in Patients with Synchronous, Solitary Brain Metastasis from Non-Small Cell Lung Cancer Treated with Radiosurgery. Int J Radiat Oncol Biol Phys 2008, in press.

  • Dhople A, Kwok L, Chin L, et al. Efficacy and Quality of Life Outcomes in Patients with Atypical Trigeminal Neuralgia Treated with Gamma Knife Radiosurgery. Int J Radiat Oncol Biol Phys 2007; 69(2): 397-403. Epub 2007 Apr 30.

  • Ma L, Kwok Y, Chin LS, Simard JM, Regine WF. Concomitant GRID Boost for Gamma Knife Radiosurgery. Medical Physics 2005 Nov; 32(11):3419-3423.

  • Ma L, Kwok Y, Chin LS, Yu C, Regine WF. Comparative Analyses of Linac and Gamma Knife Radiosurgery for Trigeminal Neuralgia Treatments. Phys Med Biol 2005 Nov 21; 50 (22): 5217-5227. Epub 2005 Oct 24.

  • Herman JM, Petit JH, Amin P, Kwok Y, Dutta PR, Chin LS: Repeat Gamma Knife Radiosurgery for Refractory or Recurrent Trigeminal Neuralgia: Treatment Outcomes and Quality of Life Assessment. Int J Rad Oncol Biol Phys 59(1):112-116, 2004.

  • Cheuk AV, Chin LS, Petit JH, Herman JM, Fang H-B, Regine WF: Imaging correlates of Gamma Knife Outcome in Trigeminal Neuralgia. Int J Rad Oncol Biol Phys 60(2):537-541, 2004.

  • Shehata MK, Young AB, Reid B, Patchell RA, St. Clair W, Sims J, Sanders M, Meigooni AS, Mohiuddin M, Regine WF. Stereotatic Radiosurgery (SRS) of 468 Brain Metastases = 2 cm: Implications for SRS Dose and Whole Brain Radiation Therapy (WBRT). Int J Radiation Oncology Biol Phys; 59(1): 87-93, 2004.

  • DiBiase SJ, Kwok Y, Yovino S, Arena C, Naqvi S, Temple R, Regine W, Amin P, Guo C, Chin LS: Factors Predicting Local Tumor Control After Gamma Knife Stereotactic Radiosurgery for Benign Intracranial Meningiomas. Int J Rad Oncol Biol Phys 60:1515-1519, 2004.

  • Jaganathan J, Balsara K, Chin LS: Long-Term Survival Following Gamma Knife Radiosurgery. Am J Clin Oncol 27:441-444, 2004.

  • K Li, and L. Ma, Selective Source Blocking for Treatment of Trigeminal Neuralgia Based on Analytical Gamma Knife Dose Modeling, Phys. Med. Biol. 49(15)3455-3463, 2004. 

  • Flannery T, Suntharalingam M, Kwok Y, Koffman B, Amin P, Chin L, Nicol B, Fowler B, Young AB, Regine W: Gamma Knife stereotactic radiosurgery for synchronous versus metachronous solitary brain metastases from non-small cell lung cancer. Lung Cancer 42: 327-333, 2003.

  • Patchell RA, Regine WF. The Rational for Adjuvant Whole Brain Radiation Therapy with Radiosurgery in the Treatment of Single Brain Metastases. Tech Ca Res Treat 2(2): 111-115, 2003.

  • M Guerrero, XA Li, and L. Ma, A Technique to Sharpen the Beam Penumbra for Gamma Knife Radiosurgery, Phys. Med. Biol. 48 1843-1853, 2003. 

  • DiBiase SJ, Chin LS: Stereotactic radiosurgery for benign neoplasms. Technol Cancer Res Treat 2:127-133, 2003.

  • Chin LS, Szerlip NJ, Regine WF: Stereotactic radiosurgery for meningiomas. Neurosurgical Focus 14:Article 6, 2003.

  • Petit JH, Herman JM, Nagda S, DiBiase SJ, Chin LS: Radiosurgery for the Treatment of Trigeminal Neuralgia: Evaluating Quality of Life and Treatment Outcomes. Int J Rad Oncol Biol Phys 56:1147-1153, 2003.

  • Shepard DM, Chin LS, DiBiase S, Naqvi S, Lim J, Ferris MC: Clinical Implementation of an Automated Planning System for Gamma Knife Radiosurgery. Int J Rad Oncol Biol Phys 56:1488-1494, 2003.

  • L. Ma, L.Chin, S. DiBiase, R. Gullapalli, A. Kennedy, and J Marc Simard, Concomitant Boost of Stratified Target Volume with Ggamma Knife Radiosurgery: a Treatment Planning Study, 26(4) 100-105e, Am. J. Clin. Oncol. 2003. 

  • Agris, J. M., Shah N, Simard MJ, Zoarski GH. Complete Occlusion of a Type IV Vein of Galen Aneurysm using both Glue Embolization and Gamma Knife Radiosurgery. ASNR 41st Annual Meeting and Symposium, Washington, DC, April 26-May 2, 2003. 

  • Nwokedi EC, DiBiase SJ, Jabbour S, Herman J, Amin P, Chin LS: Gamma Knife Stereotactic Radiosurgery for patients with glioblastoma multiforme. Neurosurgery 50:41-47, 2002.

  • DiBiase SJ, Chin LS, Ma L: Influence of Gamma Knife Radiosurgery on the quality of life in patients with brain metastases. Am J Clin Oncol (CCT) 25:131-134, 2002.

  • Ioffe V, Hudes RS, Shepard D, Simard JM, Chin LS, Yu C: Fetal and ovarian radiation dose in patients undergoing Gamma Knife radiosurgery. Surg Neurol 58:32-41, 2002.

  • S. DiBiase, L, Chin, and L. Ma, The Influence of Gamma Knife Radiosurgery on the Quality of Life in Patients with Brain Metastases, Am. J. Clin. Oncol. 25(2): 131-134, 2002. 

  • Petit JH, Hudes RS, Chen TS, Eisenberg HM, Simard JM, Chin LS: Reduced dose radiosurgery for vestibular schwannomas. Neurosurgery 49:1299-1307, 2001.

  • Ma L, Chi LS, Shepard D, Amin P, Slawson R: The effect of user-defined variables on dosimetry consistency in Gamma Knife planning. Phys Med Biol 45:N43-N47, 2000. 

  • Sansur CA, Chin LS, Ames JW, Banegura AT, Aggarawal S, Ballestros M, Amin P, Simard JM, Eisenberg HM: Gamma Knife radiosurgery for treatment of brain metastases. Stereotact Fuct Neurosurery 74:37-51, 2000. 

  • Ma L, Chin LS, Shepard D, Sarfaraz M, Yu C: Investigation of eye lens dose for Gamma Knife radiosurgery treatment of trigeminal neuralgia. J Appl Clin Med Phys 1:116-119, 2000. 

  • Ove R, Kelman S, Amin P, Chin LS: Preservation of visual fields after peri-sellar Gamma Knife radiosurgery. Int. J Cancer 90:343-350, 2000. 

  • Kondziolka D, Flickinger JC, B, and the Gamma Knife Meningioma Study Group: Judicious resection and /or radiosurgery for parasagittal meningiomas: Outcomes from a multicenter review. Neurosurgery 43:405-414, 1998. 

  • Kwok Y, Patchell RA, Regine WF. Palliation of Brain and Spinal Cord Metastases In: Principles & Practice of Radiation Oncology, 5th Edition, Lippincott, Williams and Wilkins Publishing. 2008; 1974-1985.

  • Chin LS, Ma l, DiBiase S: Radiation necrosis following Gamma Knife radiosurgery: A case-controlled comparison of treatment parameters and long-term clinical follow-up. J Neurosurg, in press. 

  • Ahn ES, Chin LS, Regine WF, Ragheb J, DiPatri AJ: Long-Term Control of an Intracranial Clear Cell Meningioma with Both Surgery and Gamma Knife Surgery. J Neurosurg, in press. 

  • Suh JH, Barnett GH, Regine WF. Stereotactic Radiosurgery for Brain Metastases. In: Chin LC, Regine WF, eds. Principles & Practice of Stereotactic Radiosurgery. Springer-Verlag Publishing. (In Press).

  • Patchell RA, Regine WF. Whole Brain Radiation Therapy for Brain Metastases. In: Chin LC, Regine WF, eds. Principles & Practice of Stereotactic Radiosurgery. Springer-Verlag Publishing. (In Press).

  • Chin LC, Regine WF, eds. Principles & Practice of Stereotactic Radiosurgery. Springer-Verlag Publishing.

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