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Es la presencia de una sustancia anormal llamada macroamilasa en la sangre.

Nombres alternativos


La macroamilasa es una sustancia que consiste en una enzima, llamada amilasa, que se fija a una proteína. Debido a que es grande, los riñones filtran la macroamilasa de la sangre muy lentamente.

La mayoría de las personas con macroamilasemia no tienen una enfermedad seria que esté causándola, pero la afección ha sido asociada con:


La macroamilasemia no causa síntomas.

Pruebas y exámenes

Un examen de sangre mostrará altos niveles de amilasa. Sin embargo, la macroamilasemia puede lucir similar a la pancreatitis aguda, que también ocasiona niveles altos de amilasa en la sangre.

La medición de los niveles de amilasa en la orina puede ayudar a diferenciar la macroamilasemia de la pancreatitis aguda. Los niveles de amilasa en la orina son bajos en personas con macroamilasemia, pero altos en pacientes con pancreatitis aguda.


Grupos de apoyo

Expectativas (pronóstico)

Posibles complicaciones

Cuándo contactar a un profesional médico



Forsmark CE. Pancreatitis. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 146.

Version Info

  • Last reviewed on 2/19/2012
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.

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This page was last updated: May 20, 2014

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