Erythroplasia of Queyrat

Toggle: English / Spanish


Erythroplasia of Queyrat is an early form of skin cancer found on the penis. The cancer is called squamous cell carcinoma in situ.


The condition is most often seen in men who have not been circumcised. It is linked to the human papillomavirus (HPV).


The main symptoms are a rash and irritation on the tip or shaft of the penis that persists. The area is most often red and does not respond to topical creams.

Exams and Tests

The health care provider will examine the penis to diagnose the condition and will perform a biopsy to make the diagnosis.


Treatment may include:

  • Skin creams such as imiquimod or 5-fluorouracil. These creams are used for several weeks to months
  • Anti-inflammatory (steroid) creams, if other medicines do not work.

If skin creams do not work, your provider may recommend other treatments such as:

  • Mohs micrographic surgery to remove the area
  • Laser surgery
  • Freezing the cancer cells (cryotherapy)
  • Scraping away cancer cells and using electricity to kill any that remain (curettage and electrodesiccation)


Habif TP. Premalignant and malignant nonmelanoma skin tumors. In: Habif TP, ed. Clinical Dermatology. 6th ed. St. Louis, MO: Elsevier; 2016:chap 21.

Regan TD, Lawrence N. Bowen's disease and erythroplasia of Querat. In: Lebwohl MG, Heymann WR, Berth-Jones J, Coulson I, eds. Treatment of Skin Disease: Comprehensive Therapeutic Strategies. 4rd ed. Philadelphia, PA: Elsevier Saunders; 2014:chap. 31.

Version Info

  • Last reviewed on 7/23/2015
  • Kevin Berman, MD, PhD, Atlanta Center for Dermatologic Disease, Atlanta, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission ( URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.