Erythroplasia of Queyrat

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Definition

Erythroplasia of Queyrat is an early form of skin cancer found on the penis. The cancer is called squamous cell carcinoma in situ.

Causes

The condition is most often seen in men who have not been circumcised. It is linked to the human papillomavirus (HPV).

Symptoms

The main symptoms are a red rash and irritation on the tip or shaft of the penis that do not go away.

Exams and Tests

Your health care provider will examine your penis and may do a biopsy to diagnose the condition.

Treatment

Treatment may include:

  • Special skin creams that are used for several weeks to months
  • Anti-inflammatory (steroid) creams, if other medicines do not work

If skin creams do not work, your doctor may recommend other treatments, such as:

  • Mohs micrographic surgery
  • Laser surgery
  • Freezing the cancer cells (cryotherapy)
  • Scraping away cancer cells and using electricity to kill any that remain (curettage and electrodesiccation)

References

Habif TP. Premalignant and malignant nonmelanoma skin tumors. In: Habif TP, ed. Clinical Dermatology. 5th ed. Philadelphia, PA: Elsevier Mosby; 2009:chap 21.

James WD, Berger TG, Elston DM. Epidermal nevi, neoplasms, and cysts. In: James WD, Berger TG, Elston DM, eds. Andrews' Diseases of the Skin: Clinical Dermatology. 11th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 29.

Regan TD, Lawrence N. Bowen's disease and erythroplasia of Querat. In: Lebwohl MG, Heymann WR, Berth-Jones J, Coulson I, eds. Treatment of Skin Disease: Comprehensive Therapeutic Strategies. 4th ed. Philadelphia, PA: Elsevier Saunders; 2013:chap. 31.

Version Info

  • Last reviewed on 11/14/2014
  • Richard J. Moskowitz, MD, dermatologist in private practice, Mineola, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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