Citric acid urine test

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Definition

Citric acid urine test measures the level of citric acid in urine.

Alternative Names

Urine - citric acid test

How the Test is Performed

You will need to collect your urine at home over 24 hours. Your health care provider will tell you how to do this. Follow instructions exactly so that the results are accurate.

How to Prepare for the Test

No special preparation is necessary for this test. But the results are affected by your diet, and this test is usually done while you are on a normal diet. Ask your provider for more information.

How the Test will Feel

The test involves only normal urination, and there is no discomfort.

Why the Test is Performed

The test is used to diagnose

and evaluate stone disease.

Normal Results

The normal range is 320 to 1,240 mg per 24 hours.

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results.

What Abnormal Results Mean

A low level of citric acid may mean renal tubular acidosis and a tendency to form calcium kidney stones.

The following may decrease urine citric acid levels:

  • Chronic kidney failure
  • Diabetes
  • Excessive muscle activity
  • Medicines called angiotensin converting enzyme inhibitors (ACE inhibitors)
  • Parathyroid glands do not produce enough of its hormone (hypoparathyroidism)
  • Too much acid in the body fluids (acidosis)

The following may increase urine citric acid levels:

Risks

There are no risks with this test.

References

McPherson RA, Ben-Ezra J. Basic examination of urine. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 28.

Sreedharan R, Avner ED. Renal tubular acidosis. In: Kliegman RM, Stanton BF, St Geme JW III, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2015:chap 529.

Version Info

  • Last reviewed on 10/13/2015
  • Walead Latif DO, Nephrologist, Medical Director of Fresenius Vascular Care, and Clinical Assistant Professor of Rutgers Medical School, Newark, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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