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Caplan syndrome is swelling (inflammation) and scarring of the lungs in people with
who have been exposed to mining dust containing coal. The lung disease is called .
Causes, incidence, and risk factors
Caplan syndrome is caused by breathing in coal mining dust. This causes inflammation and can lead to the development of many small lung lumps (nodules) and mild asthma-like airway disease.
Some people who have been exposed to the dust have severe lung scarring that makes it difficult for their lungs to carry oxygen to the bloodstream (called progressive massive fibrosis). People with rheumatoid arthritis do not seem more likely to have this complication of scarring.
Caplan syndrome is very rare in the United States.
Signs and tests
Your health care provider will take a detailed medical history that will include questions about your jobs (past and present) and other possible sources of exposure to mining dust. The health care provider will also do a physical exam, paying special attention to any joint and skin disease.
Other tests can include:
There is no specific treatment for Caplan syndrome, other than treating any lung and joint disease.
Attending support groups with other people who have similar diseases can help you understand your disease and adjust to its treatment and other lifestyle changes.
Caplan syndrome rarely causes serious breathing trouble or disability due to lung problems.
- Increased risk for tuberculosis
- Progressive massive fibrosis (scarring)
- Side effects of medications
Calling your health care provider
Call for an appointment with your health care provider if you have symptoms of Caplan syndrome.
People with rheumatoid arthritis should avoid exposure to hazardous dust.
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Cowie RL, Murray J, Becklake MR. Pneumoconioses and other mineral dust-related diseases. In: Mason RJ, Broaddus VC, Martin TR, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa: Saunders Elsevier; 2010:chap 65.
Raghu G. Interstitial lung disease. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 92.
Samet JM. Occupational pulmonary disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap93.
- Last reviewed on 5/30/2013
- Denis Hadjiliadis, MD, Assistant Professor of Medicine, Division of Pulmonary, Allergy and Critical Care, University of Pennsylvania, Philadelphia, PA. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.
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This page was last updated: May 20, 2014