Toggle: English / Spanish
A buccal (pronounced "buckle") smear is the painless removal of a sample of cells from the inside of your mouth (cheek) for study.
Sex chromatin test
How the test is performed
The health care provider will gently scrape the inside of the cheek with a small spatula to collect cells for testing. Sometimes, you can do this yourself.
How to prepare for the test
Rinse and wash the mouth as instructed.
How the test will feel
You will feel a scraping sensation as cells are removed from the cheek.
Why the test is performed
This test is done to get cells for chromosome or DNA analysis, most often for genetic testing.
The International Olympic Committee adopted the test many years ago to help detect male imposters among female athletes. When the test is used in this way, it's called the sex chromatin test.
This test may also help establish the sexual identity of newborns.
What abnormal results mean
What the risks are
There are no risks.
- Last reviewed on 1/4/2013
- Chad Haldeman-Englert, MD, Wake Forest School of Medicine, Department of Pediatrics, Section on Medical Genetics, Winston-Salem, NC. Review provided by VeriMed Healthcare Network. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, and Stephanie Slon.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.