Vigabatrin (By mouth)

Introduction

Vigabatrin (vye-GA-ba-trin)

Treats seizures (epilepsy). This medicine is an anticonvulsant.

Brand Name(s)

Sabril

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you or your child have had an allergic reaction to vigabatrin.

How to Use This Medicine

Liquid, Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
  • You may take this medicine with or without food.
  • To use the oral liquid:
    • Open the packet and empty the contents into an empty cup. Your doctor will tell you how many packets to use for each dose.
    • Mix the powder with water (cold or room temperature) using an oral syringe to measure the proper amount. Your doctor will tell you how much water to use.
    • Give the proper amount of liquid to your child. Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
  • This medicine may be used together with other seizure medicines. Keep using all of your medicines unless your doctor tells you to stop.
  • This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using clonazepam (Klonopin®), fosphenytoin (Cerebyx®), or phenytoin (Dilantin®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or planning to become pregnant, or breastfeeding. Your doctor may want you to join a pregnancy registry for patients taking seizure medicines.
  • Make sure your doctor knows if you or your child have kidney disease, anemia, depression, eye or vision problems, mental illness, or nerve problems (neuropathy or numbness).
  • This medicine may increase your risk of permanent vision loss. Check with your doctor right away if blurred vision, difficulty with reading, or any other change in vision occurs during or after treatment. Your doctor may want you or your child to be checked by an eye doctor.
  • This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you, your child, or your caregiver notice any of these side effects, tell your doctor right away.
  • Do not stop using this medicine suddenly without asking your doctor. You may need to slowly decrease your dose before stopping it completely.
  • This medicine may make you drowsy, sleepy, or weak. Avoid driving, using machines, or doing anything else that could be dangerous if you are drowsy or not alert.
  • Check with your doctor right away if you or your child are having burning, numbness, tingling, or painful sensations in the arms, hands, legs, or feet. These could be symptoms of a condition called peripheral neuropathy.
  • Tell your doctor if you or your child have an increase in weight or swelling in the hands, ankles, or feet while taking this medicine.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision or changes in vision.
  • Change in how much or how often you urinate.
  • Feeling sad, depressed, or unusual mood or behavior.
  • Fever, chills, cough, sore throat, and body aches.
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet.
  • Swelling in your hands, ankles, or feet.
  • Thoughts of hurting or killing oneself or others.
  • Tremors.
  • Unusual bleeding or bruising.
  • Unusual tiredness or weakness.
  • Weight gain.

If you notice these less serious side effects, talk with your doctor:

  • Back pain.
  • Constipation, diarrhea, nausea, or vomiting.
  • Headache or dizziness.
  • Joint or muscle pain.
  • Stuffy or runny nose.
  • Unusual drowsiness or sleepiness.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: June 18, 2013

         
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