Tolbutamide (By mouth)

Introduction

Tolbutamide (tole-BUE-ta-mide)

Treats diabetes mellitus. Belongs to a class of drugs called sulfonylureas.

Brand Name(s)

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have ever had an allergic reaction to tolbutamide or other sulfonylurea drugs such as Tolinase®, chlorpropamide, or Glucotrol®. You should not use this medicine if you are pregnant.

How to Use This Medicine

Tablet

  • Your doctor will tell you how much to take and how often.

If a dose is missed:

  • Take the missed dose as soon as possible.
  • Skip the missed dose if it is almost time for your next regular dose.
  • You should not use two doses at the same time.

How to Store and Dispose of This Medicine

  • Store at room temperature, away from heat, moisture, and direct light.
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Avoid drinking alcohol while you are taking this medicine.
  • While using this medicine, avoid taking aspirin or cough and cold medicines.
  • Tolbutamide interacts with many medicines. Before you start taking tolbutamide, make sure your doctor knows of all other medicines you are taking.

Warnings While Using This Medicine

  • Talk with your doctor before taking this medicine if you are breastfeeding or if you have liver, kidney, or heart disease, G-6-PD deficiency, or a thyroid disorder.
  • To control your diabetes, follow the diet that your doctor orders and take this medicine on a regular schedule.
  • You may have low blood sugar while you are taking tolbutamide, especially if you miss a meal, exercise for a long time, or drink alcohol. Symptoms of low blood sugar include sweating, feeling very hungry, fast heartbeat, drowsiness, confusion, headache that won't go away, chills, or vomiting.
  • Ask your doctor what you should do in case you have low blood sugar. You will need to control it quickly.
  • Make sure your doctor knows you are taking this medicine before you have any kind of surgery.
  • This medicine may make your skin sensitive to sunlight. Use a sunscreen when outdoors. Avoid sunlamps or tanning beds.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Unexplained fever, chills or sore throat
  • Unusual bleeding or bruising
  • Yellowing of skin or eyes
  • Dark colored urine or light colored stools
  • Severe skin rash or hives

If you notice these less serious side effects, talk with your doctor:

  • Mild nausea or vomiting
  • Sensitivity of skin to sunlight
  • Skin rash or itching

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch)

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

This page was last updated: June 18, 2013

         
Average rating (0)