Pseudoephedrine/triprolidine (By mouth)
Pseudoephedrine (soo-doe-e-FED-rin), Triprolidine (trye-PROE-li-deen)
Treats runny nose, nasal congestion, sneezing, and itchy or watery eyes caused by hay fever or the common cold. This medicine is a combination of an antihistamine and a decongestant.
Silafed, Trip-Pse, Hist-PSE Drops, Pediatex TD, Nasal Decongestant/Antihistamine, Triphed, Pseudocot-T, Aprodine, Trisudrine
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not use this medicine if you have had an allergic reaction to pseudoephedrine or triprolidine. You should not use this medicine if you have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days. Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years old. Using these medicines in very young children might cause serious or possibly life-threatening side effects.
How to Use This Medicine
- Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- If you are using this medicine without a prescription, follow the instructions on the medicine label.
- Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not refrigerate or freeze the liquid form of this medicine.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Tell your doctor if you are using any medicines that make you sleepy. These include sleeping pills, cold and allergy medicine, narcotic pain relievers, and sedatives.
- Do not drink alcohol while you are using this medicine.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding.
- Tell your doctor if you have diabetes, thyroid problems, high blood pressure, glaucoma, an enlarged prostate, or a history of heart disease.
- This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
- Do not give this medicine to a child under 6 years of age unless your doctor tells you to.
- If your symptoms do not improve within 7 days or if they get worse, call your doctor.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Fast, pounding, or uneven heartbeat.
If you notice these less serious side effects, talk with your doctor:
- Trouble sleeping.
- Feelings of restlessness or excitement (especially in children).
- Loss of appetite.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last Reviewed on 06/12/2013
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This page was last updated: September 18, 2013