Propofol (By injection)

Introduction

Propofol (PROE-poe-fol)

Used as a sedative and anesthetic before and during surgery and other medical procedures. Causes relaxation and sleepiness.

Brand Name(s)

Amerinet Choice Propofol, Diprivan, Diprivan Novaplus, Fresenius Propoven, Novaplus Propofol, PremierPro RX Diprivan

When This Medicine Should Not Be Used

How to Use This Medicine

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • You will receive this medicine in a hospital or surgery center. A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have diabetes, kidney disease, heart problems, pancreas problems, or high cholesterol. Make sure your doctor knows if you have a history of head injury, stroke, or seizures (including epilepsy).
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash; itching; swelling of the face, tongue, and throat; trouble breathing; or chest pain after you get the injection.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Confusion, weakness, or numbness or tingling in your hands, feet, or lips.
  • Decrease in how much or how often you urinate.
  • Fever, chills, cough, sore throat, and body aches.
  • Lightheadedness or fainting (after you awake from surgery).
  • Lower back or side pain.
  • Muscle pain, tightness, or weakness.
  • Pain or fullness in your upper stomach.
  • Seizures.
  • Shortness of breath, cold sweat, and bluish-colored skin.
  • Slow, fast, or irregular heartbeat.
  • Swelling in your hands, ankles, or feet.

If you notice these less serious side effects, talk with your doctor:

  • Mild nausea or vomiting.
  • Pain, burning, stinging, swelling, blistering, or skin changes where the needle is placed.
  • Skin rash or itching.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 10/12/2016

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch)

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.