Phentolamine (Injection)

Introduction

Phentolamine (fen-TOL-a-meen)

Prevents and controls high blood pressure during surgery. Prevents and treats skin injury caused by norepinephrine injection. Used during a medical test or procedure to diagnose pheochromocytoma (an adrenal gland tumor). May also be used to reverse the effects of anesthesia.

Brand Name(s)

OraVerse

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not receive this medicine if you have had an allergic reaction to phentolamine, or if you have certain types of heart problems such as angina (chest pain) or a history of heart attack.

How to Use This Medicine

Injectable

  • This medicine is given through a needle placed in one of your veins or given as a shot into one of your muscles. This medicine may also be injected in your oral cavity after a dental procedure.
  • A dentist, nurse, or other trained health professional will give you this medicine.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using blood pressure medicine such as atenolol, hydrochlorothiazide (HCTZ), lisinopril, metoprolol, quinapril, Accupril®, Cozaar®, Diovan®, Lotrel®, Norvasc®, Toprol®, or Zestril®.
  • Tell your doctor if you are using pain or arthritis medicine such as aspirin, ibuprofen, naproxen, Advil®, Aleve®, Ecotrin®, or Motrin®.
  • Tell your doctor if you are using any medicines that make you sleepy. These include sleeping pills, cold and allergy medicine, narcotic pain relievers, and sedatives.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have untreated high blood pressure or heart rhythm problems.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain.
  • Dizziness or weakness.
  • Fast or uneven heartbeat.
  • Lightheadedness or fainting.
  • Problems with vision, speech, or walking.

If you notice these less serious side effects, talk with your doctor:

  • Headache or stuffy nose.
  • Nausea, vomiting, or diarrhea.
  • Warmth or redness in your face, neck, arms, or upper chest.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: June 18, 2013

         
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