Pertuzumab (Injection)

Introduction

Pertuzumab (per-TOOZ-ue-mab)

Treats breast cancer. Used together with other cancer medicines. This medicine is a monoclonal antibody.

Brand Name(s)

Perjeta

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not receive this medicine if you have had an allergic reaction to pertuzumab or if you are pregnant.

How to Use This Medicine

Injectable

  • Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
  • You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.

If a dose is missed:

  • This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine

  • Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.You should also use an effective form of birth control for 6 months after your last dose of this medicine.
  • Make sure your doctor knows if you are breastfeeding or if you have congestive heart failure, high blood pressure that is not controlled, or heart rhythm problems.
  • Your doctor will test your heart before you start treatment. The test will be repeated every few months while you receive this medicine. Contact your doctor right away if you have chest pain, trouble breathing, rapid weight gain, or swelling. These could be symptoms of heart failure.
  • This medicine may cause a serious infusion reaction that requires immediate medical attention. Tell your doctor right away if you have a fever, chills, chest pain, a headache, pain, nausea, vomiting, trouble breathing, or weakness within a few hours after the infusion.
  • Cancer medicines can cause nausea and/or vomiting in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these side effects.
  • Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fever, chills, vomiting, or headache
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet
  • Sores or white patches on your lips, mouth, or throat
  • Swelling in your hands, ankles, or feet
  • Trouble breathing, cold sweats, or bluish-colored skin
  • Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

  • Decreased appetite
  • Diarrhea
  • Hair thinning or loss
  • Nausea
  • Rash
  • Tiredness

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: September 18, 2013

         
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