Neostigmine (By mouth)

Introduction

Neostigmine (nee-oh-STIG-meen)

Treats myasthenia gravis.

Brand Name(s)

Prostigmin Bromide

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not receive this medicine if you have had an allergic reaction to neostigmine or bromides, or if you have a blockage in your intestines or urinary tract.

How to Use This Medicine

Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
  • Your doctor may ask you to keep a record of how this medicine effects you. This will help to determine if your dosing schedule needs to be changed.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using antibiotics, medicines for heart rhythm problems, or anesthetics.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding. Tell your doctor if you have asthma, heart rhythm problems, seizures (epilepsy), overactive thyroid, or stomach problems.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast, slow, or uneven heartbeat.
  • Lightheadedness or fainting.
  • Seizures.
  • Severe muscle weakness with slow, shallow breathing.
  • Twitching, or muscle movements you cannot control.

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea, stomach cramps, gas, nausea, or vomiting.
  • Dizziness or weakness.
  • Headache.
  • Increased saliva, watery eyes, runny nose.
  • Increased sweating.
  • Joint pain, muscle cramps.
  • Mild skin rash or itching.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: June 18, 2013

         
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