Moxifloxacin (By mouth)
Treats bacterial infections. This medicine is a fluoroquinolone antibiotic.
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not use this medicine if you have had an allergic reaction to moxifloxacin or to any other fluoroquinolone antibiotic (such as ciprofloxacin, gatifloxacin, levofloxacin, norfloxacin, ofloxacin, Cipro®, Floxin®, Levaquin®, Noroxin®, or Zymaxid®).
How to Use This Medicine
- Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- Take this medicine at the same time each day.
- Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.
- You may take this medicine with or without food. Swallow the tablet whole with a glass of water. Do not split, crush or chew it.
- If you use antacids, didanosine (Videx®), sucralfate (Carafate®), or mineral supplements and multivitamins with calcium, iron, or zinc, take moxifloxacin at least 4 hours before or 8 hours after these medicines.
- Drink plenty of fluids while you are being treated with this medicine. This will help prevent some side effects of moxifloxacin.
- This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you use a steroid medicine (such as dexamethasone, prednisolone, prednisone, or Medrol®). Your chance of tendon problems may increase if you use this medicine together with steroids.
- Make sure your doctor knows if you use arsenic trioxide (Trisenox®), a blood thinner (such as warfarin, Coumadin®, or Jantoven®), cisapride (Propulsid®), erythromycin (Ery-Tab®), medicine for depression (such as amitriptyline, doxepin, fluoxetine, nortriptyline, Elavil®, Pamelor®, or Sinequan®), medicine for mental illness (such as Geodon®, Haldol®, Mellaril®, or Serentil®), pain medicine (such as diclofenac, etodolac, ibuprofen, indomethacin, nabumetone, naproxen, piroxicam, Feldene®, Relafen®, or Voltaren®), or medicine for an abnormal heart rhythm (such as amiodarone, disopyramide, dofetilide, procainamide, quinidine, sotalol, Betapace®, Corvert®, Norpace®, Procanbid®, or Tikosyn®).
- Make sure your doctor knows if you use antacids (Maalox®, Mylanta®), didanosine (Videx®), sucralfate (Carafate®), or mineral supplements and multivitamins with calcium, iron, or zinc.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding or if you have a history of heart disease, heart rhythm problems, kidney disease, liver disease, myasthenia gravis, low blood potassium, depression, or a seizure disorder. Tell your doctor if you have a family history of a heart condition called prolonged QT interval.
- This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.
- This medicine may rarely cause inflammation or tearing of a tendon (the cord that attaches muscles to bones). This can occur while you are taking the medicine or after you finish taking it. The risk of tendon problems may be increased if you are older than 60 years of age, use steroid medicines (such as dexamethasone, prednisolone, prednisone, or Medrol®), have severe kidney problems, have a history of tendon problems (such as rheumatoid arthritis), or have received an organ transplant (such as heart, kidney, or lung). Stop using this medicine and check with your doctor right away if you have sudden pain or swelling in a tendon after exercise (such as ankle, back of the knee or leg, shoulder, elbow, or wrist), bruise more easily after an injury, or are not able to put weight on or move the affected area. Do not exercise until your doctor says it is all right.
- If you have severe diarrhea, ask your doctor before taking any medicine to stop the diarrhea. It may occur 2 months or more after you stop taking this medicine.
- This medicine may make you dizzy. Do not drive, use machines, or do anything else that could be dangerous until you know how this medicine affects you.
- Use this medicine only to treat the infection your doctor has prescribed it for. Do not use this medicine for any infection that has not been checked by a doctor.
- If your symptoms do not improve or if they get worse, call your doctor.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, itching, or red skin rash
- Chest pain, fast or uneven heartbeat
- Diarrhea that may contain blood
- Lightheadedness, dizziness, or fainting
- Numbness, tingling, weakness, or burning pain in your hands, arms, legs, or feet
- Pain, swelling, or bruising in your knee, ankle, shoulder, elbow, hand, or wrist
- Severe muscle weakness
- Swelling of your face, neck, or lips
- Trouble breathing
- Yellowing of your skin or the whites of your eyes
If you notice these less serious side effects, talk with your doctor:
- Agitation, confusion, or trouble sleeping
- Mild diarrhea, nausea, stomach pain, or vomiting
- Mild skin rash
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last Reviewed on 06/12/2013
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This page was last updated: September 18, 2013