Metyrosine (By mouth)

Introduction

Metyrosine (me-TYE-roe-seen)

Treats symptoms caused by pheochromocytoma (tumor of the adrenal gland). Used before surgery that removes adrenal gland tumors.

Brand Name(s)

Demser

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not take this medicine if you have had an allergic reaction to metyrosine (Demser®).

How to Use This Medicine

Capsule

  • Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
  • Drink extra liquids so you will pass more urine while you are taking this medicine. This will keep crystals from forming in your urine.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Keep all medicine away from children and never share your medicine with anyone.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using phenothiazines, such as prochlorperazine, Compazine®, Mellaril®, Phenergan®, Thorazine®, or Trilafon®, or if you are also using haloperidol (Haldol®).
  • Tell your doctor if you are using any medicines that make you sleepy. These include sleeping pills, cold and allergy medicine, narcotic pain relievers, and sedatives.
  • Avoid drinking alcohol while you are using this medicine.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have heart, kidney, or liver problems.
  • This medicine may make you drowsy. Avoid driving, using machines, or doing anything else that may be dangerous if you are not alert.
  • Make sure any doctor who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.
  • Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.
  • After you have stopped using this medicine, you may have trouble falling asleep at night and have an unusually high energy level. These feelings may last for 2 or 3 days.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

If you notice these less serious side effects, talk with your doctor:

  • Bleeding or bruising easily.
  • Blood in your urine, or painful urination.
  • Difficulty speaking.
  • Drooling, or dry mouth.
  • Feeling unusually sleepy or tired.
  • Feeling unusually sad, anxious, or confused.
  • Headache.
  • Men: unable to have or keep an erection.
  • Nausea, stomach pain, vomiting, or diarrhea.
  • Seeing or hearing things that are not there.
  • Shaking or twitching of your hands or other body parts.
  • Stuffy nose.
  • Swelling or tenderness in your hands or feet.
  • Swollen breasts, or liquid discharge from your nipples.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: June 18, 2013

         
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