Metoprolol (By mouth)

Introduction

Metoprolol (met-oh-PROE-lol)

Treats high blood pressure, angina (chest pain), and heart failure. A lower blood pressure can reduce the risk of strokes and heart attacks. This medicine is a beta-blocker.

Brand Name(s)

Toprol XL, Lopressor, Hypertensolol, Toprol-XL

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

Do not use this medicine if you have had an allergic reaction to metoprolol or any beta-blocker medicine (such as atenolol, propranolol, Corgard®, Inderal®, Tenormin®). Do not use this medicine if you have certain blood circulation problems or heart problems. Talk with your doctor about what these problems are.

How to Use This Medicine

Tablet, Long Acting Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
  • It is best to take this medicine with food or milk.
  • Carefully follow your doctor's instructions about any special diet.
  • Do not crush or chew the extended-release tablet.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using clonidine (Catapres®), digoxin (Lanoxin®), reserpine, medicine to treat depression (such as bupropion, fluoxetine, paroxetine, Paxil®, Prozac®, Wellbutrin®), an MAO inhibitor (such as Eldepryl®, Marplan®, Nardil®, Parnate®), medicine to treat mental illness (such as thioridazine, Mellaril®), medicine for heart rhythm problems (such as propafenone, quinidine, Rhythmol®), medicine to treat HIV or AIDS (such as ritonavir, Norvir®), an allergy medicine (such as diphenhydramine, Benadryl®), medicine to treat malaria (such as hydroxychloroquine, quinidine, Plaquenil®), medicine to treat a fungus infection (such as terbinafine, Lamisil®), or a stomach medicine (such as cimetidine, Tagamet®).
  • Make sure your doctor knows if you are also using other blood pressure medicines (such as diltiazem, verapamil, Calan®, Cardizem®, Isoptin®, Verelan®) or a diuretic (water pill, such as furosemide, hydrochlorothiazide, torsemide, Demadex®, Lasix®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have lung disease (such as asthma), kidney disease, liver disease, blood vessel or circulation problems, diabetes, low blood pressure, an overactive thyroid, diabetes, or an adrenal gland tumor (pheochromocytoma). Tell your doctor if you have a history of allergies.
  • Do not stop using this medicine suddenly without asking your doctor. You may need to slowly decrease your dose before stopping it completely.
  • Call your doctor right away if you have rapid weight gain or trouble breathing. These may be signs of a worsening heart problem.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests.
  • This medicine could lower your blood pressure too much and cause you to feel dizzy or lightheaded. Stand or sit up slowly if you are dizzy. This is more likely to happen when you begin to use the medicine or if you become dehydrated.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else until you know how this medicine affects you.
  • Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in normal range. You may have to take blood pressure medicine for the rest of your life.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fever, chills, cough, sore throat, and body aches
  • Lightheadedness, dizziness, or fainting
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Slow, fast, pounding, or uneven heartbeat
  • Trouble breathing, cold sweats, and bluish-colored skin
  • Unusual bleeding or bruising
  • Worsening chest pain

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea
  • Feeling dizzy or drowsy

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: June 18, 2013

         
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