Maraviroc (By mouth)

Introduction

Maraviroc (mar-a-VIR-ok)

Treats human immunodeficiency virus (HIV) infection. HIV causes acquired immune deficiency syndrome (AIDS). This medicine does not cure HIV or AIDS, but combinations of drugs that treat HIV infection may slow the progress of the disease. This medicine is usually given to patients who have received HIV treatment in the past.

Brand Name(s)

Selzentry

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to maraviroc, or if you have severe kidney disease and are taking certain other medicines.

How to Use This Medicine

Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
  • This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one.
  • Maraviroc is used with other medicines to treat HIV infection. Make sure you take all of the medicines your doctor ordered. Do not stop taking this medicine, even for a short time, unless your doctor tells you to.
  • This medicine works best if there is a constant amount in the blood. To keep blood levels constant, take this medicine at the same time each day and do not miss any doses. Refill your prescription on time so you do not run out of medicine.
  • You may take this medicine with or without food.
  • Swallow the tablet whole. Do not crush, break, or chew it.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If your next regular dose is less than 6 hours away, wait until then to use the medicine and skip the missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using St John's wort, clarithromycin (Biaxin®), itraconazole (Sporanox®), ketoconazole (Nizoral®), nefazodone (Serzone®), rifampin (Rifadin®, Rimactane®), telithromycin (Ketek®), medicine to treat seizures (such as carbamazepine, phenobarbital, phenytoin, Carbatrol®, Dilantin®, or Tegretol®), or other medicines to treat HIV or AIDS (such as atazanavir, darunavir, delavirdine, efavirenz, etravirine, fosamprenavir, indinavir, lopinavir/ritonavir, nelfinavir, ritonavir, saquinavir, Crixivan®, Intelence®, Invirase®, Kaletra®, Norvir®, Lexiva®, Prezista®, Rescriptor®, Reyataz®, Sustiva®, or Viracept®).
  • Make sure your doctor knows if you are also using medicine to lower blood pressure. Some blood pressure medicines are atenolol, hydrochlorothiazide (HCTZ), lisinopril, metoprolol, quinapril, Accupril®, Benicar®, Cozaar®, Diovan®, Lotrel®, Norvasc®, Toprol®, Zestril®.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant, or if you have kidney disease, liver disease (including hepatitis B or C), heart disease, or low blood pressure.
  • You should not breastfeed if you have HIV or AIDS, because you might give the infection to your baby through your breast milk.
  • Your immune system may get stronger when you start taking HIV medicines. Tell your doctor right away if you notice any changes in your health. Sometimes the immune system will start to fight infections that were hidden in your body, such as pneumonia, herpes, or tuberculosis.
  • Stop using this medicine and check with your doctor right away if you have a rash with fever, pain in the upper stomach, dark urine, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious and life-threatening liver problem. This liver problem sometimes starts with an allergic reaction.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert. Stand or sit up slowly if you feel lightheaded or dizzy.
  • This medicine may increase your risk of infections or cancer. Talk to your doctor if you have concerns about this risk.
  • This medicine will not keep you from giving HIV to your partner during sex. Make sure you understand and practice safe sex, even if your partner also has HIV. Do not share needles with anyone.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments. Blood tests may be needed to check for unwanted effects.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain
  • Dark-colored urine or pale stools
  • Dizziness, lightheadedness, or faintness when getting up suddenly from a lying or sitting position
  • Nausea, vomiting, loss of appetite, or pain in your upper stomach
  • Severe skin rash
  • Yellowing of your skin or the whites of your eyes

If you notice these less serious side effects, talk with your doctor:

  • Constipation, diarrhea, or stomach pain or upset
  • Fever, chills, cough, runny or stuffy nose, sore throat, and body aches
  • Mild skin rash

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: September 18, 2013

         
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