Linagliptin (By mouth)

Introduction

Linagliptin (lin-a-GLIP-tin)

Used together with proper diet and exercise to control blood sugar levels in patients with type 2 diabetes.

Brand Name(s)

Tradjenta

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to linagliptin. This medicine should not be used in patients with type 1 diabetes or diabetic ketoacidosis (high ketones and acid in the blood).

How to Use This Medicine

Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
  • You may take this medicine with or without food.
  • Carefully follow your doctor's instructions about any special diet or exercise program.
  • This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using insulin or other medicines to treat your diabetes (such as glipizide, glimepiride, glyburide, tolbutamide, Amaryl®, DiaBeta®, Glucotrol®, Glynase®, Micronase®, or Orinase®). Tell your doctor if you are using rifampin (Rifadin®, Rimactane®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease or liver disease.
  • Tell your doctor if you have a fever, an infection, or an injury, or if you are planning to have surgery. Your doctor may need to change your dose of linagliptin.
  • Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments. You will also need to check your blood sugar regularly at home.
  • This medicine is only part of a complete program for controlling diabetes. It is important that you always eat a healthy diet, watch your weight, and get regular exercise.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast heartbeat, cold sweats, or shakiness.
  • Lightheadedness, dizziness, or hunger.
  • Severe drowsiness, confusion, or mental changes.
  • Sudden and severe stomach pain, nausea, vomiting, or loss of appetite.
  • Unusual tiredness or weakness.

If you notice these less serious side effects, talk with your doctor:

  • Back, joint, or muscle pain.
  • Headache.
  • Skin rash.
  • Sore throat.
  • Stuffy or runny nose.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: June 18, 2013

         
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