Improves breathing in people with a condition called Hurler or Hurler-Scheie mucopolysaccharidosis I (MPS I).
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not receive this medicine if you have had an allergic reaction to laronidase.
How to Use This Medicine
- Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
- A nurse or other trained health professional will give you this medicine.
- This medicine is usually given once per week. The medicine is injected slowly and the needle will remain in place for up to 4 hours.
- You may be given other medicines to keep you from developing a fever or skin reaction to laronidase.
If a dose is missed:
- This medicine needs to be given on a fixed schedule. If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breast feeding.
- Tell your doctor if you have heart disease or liver disease.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain.
- Dark-colored urine or pale stools.
- Fever, chills, cough, sore throat, and runny or stuffy nose.
- Lightheadedness or fainting.
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet.
- Swelling in your hands, ankles, or feet.
- Unusual bleeding, bruising, or weakness.
- Yellowing of your skin or the whites of your eyes.
If you notice these less serious side effects, talk with your doctor:
- Muscle tightness or spasms.
- Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.
- Warmth or redness in your face, neck, or chest.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last Reviewed on 06/12/2013
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