Ipilimumab (Injection)

Introduction

Ipilimumab (ip-i-LIM-ue-mab)

Treats skin cancer (melanoma).

Brand Name(s)

Yervoy

When This Medicine Should Not Be Used

How to Use This Medicine

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the needle will remain in place for at least 90 minutes.
  • A nurse or other health provider will give you this medicine.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine

  • Tell your doctor if you are pregnant or breastfeeding, or if you have adrenal gland problems, pituitary gland problems, thyroid problems, an autoimmune disease (such as Crohn disease, lupus, or sarcoidosis), kidney disease, liver disease, or stomach or bowel problems (such as colitis).
  • This medicine may cause the following problems:
    • Colitis (inflammation of the colon)
    • Liver problems
    • Serious skin reactions
    • Muscle and nerve problems
    • Adrenal, pituitary, or thyroid gland problems
    • Eye problems
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. You may also need blood tests to check for side effects.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision, difficulty reading, eye pain, or other vision changes
  • Blistering, peeling, red skin rash
  • Chest pain, shortness of breath, swelling in your hands, ankles, or feet
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, or pain in your upper stomach, yellow skin or eyes
  • Diarrhea that may contain blood
  • Fever, chills, cough, sore throat, and body aches
  • Lightheadedness, dizziness, or fainting
  • Muscle pain, tenderness, or weakness
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet
  • Shortness of breath, tiredness, coughing
  • Sores, ulcers, or white spots in your mouth or on your lips
  • Vomiting blood or material that looks like coffee grounds
  • Weakness, headaches, tiredness, weight changes, or feeling cold

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea
  • Mild skin rash
  • Pain, itching, burning, swelling, bleeding, or a lump under your skin where the needle was placed

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 12/4/2015

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