Gadoteridol (Injection)

Introduction

Gadoteridol (gad-oh-TER-i-dol)

Used as a contrast agent for magnetic resonance imaging (MRI) scans. MRI scans create images or "pictures" of the brain, spine, head, or neck. This medicine is a gadolinium-based contrast agent (GBCA).

Brand Name(s)

Prohance

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not receive this medicine if you or your child have had an allergic reaction to gadoteridol or other gadolinium-based contrast agents.

How to Use This Medicine

Injectable

  • A nurse or other trained health professional will give you this medicine.
  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.This medicine is given just before you have an MRI scan.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, anemia, sickle cell anemia, asthma, diabetes, high blood pressure (hypertension), or a history of seizures.
  • Check with your doctor or nurse right away if you or your child have burning or itching of the skin; deep bone pain in the hips or ribs; joint stiffness; a limited range of motion in the arms and legs; muscle weakness; red or dark patches on the skin of the arms or legs; or skin swelling, hardening, or tightening within the first few days or weeks after you receive this medicine. These may be symptoms of a very serious disease called nephrogenic systemic fibrosis (NSF).
  • This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Check with your doctor or nurse right away if you or your child have chest pain; cold, clammy skin; confusion; dizziness; lightheadedness; a skin rash; itching; sweating; swelling of the face, tongue, and throat; or trouble with breathing after you receive the medicine.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, or blood in your urine.
  • Chest pain.
  • Confusion, restlessness, or increased salivation.
  • Fast, slow, pounding, or uneven heartbeat.
  • Fever.
  • Lightheadedness, dizziness, or fainting.
  • Muscle stiffness, weakness, stiff joints, trouble with moving, or deep bone pain.
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet.
  • Rash or redness of the skin.
  • Shortness of breath or troubled breathing.
  • Swelling, hardness, tightness, burning, itching, or red or dark patches on the skin.
  • Warmth or redness in your face, neck, arms, or upper chest.

If you notice these less serious side effects, talk with your doctor:

  • Anxiety.
  • Bad taste in your mouth.
  • Dry mouth, nausea, vomiting, diarrhea, or stomach cramps.
  • Headache.
  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.
  • Ringing in the ears or watery eyes
  • Stuffy or runny nose.
  • Weakness or tiredness.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: September 18, 2013

         
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