Fosinopril/hydrochlorothiazide (By mouth)

Introduction

Fosinopril (fos-IN-oh-pril), Hydrochlorothiazide (hye-droe-klor-oh-THYE-a-zide)

Treats high blood pressure.

Brand Name(s)

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to fosinopril, hydrochlorothiazide, other ACE inhibitors like captopril, enalapril, lisinopril, Accupril®, Altace®, Lotensin®, Lotrel®, Monopril®, Prinivil®, Zestoretic®, or Zestril®, , or to sulfa drugs. You should not use this medicine if you are pregnant, if you have asthma, or if you are not able to urinate.

How to Use This Medicine

Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
  • Drink extra fluids so you will pass more urine while you are using this medicine. This will keep your kidneys working well and help prevent kidney problems.

If a dose is missed:

  • This medicine needs to be given on a fixed schedule. If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • There are many other drugs that interact with this medicine. Make sure your doctor knows all other medicines you are using.
  • Make sure your doctor knows if you are using pain or arthritis medicine, medicines to lower blood cholesterol or triglycerides. Tell your doctor if you are taking other diuretics ("water pills"), diabetes medicines, antacid medicines, lithium, steroids, insulin, or medicines for diabetes.

Warnings While Using This Medicine

  • Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
  • Make sure your doctor knows if you are breast feeding.
  • Make sure your doctor knows if you have lupus, asthma, heart disease, liver disease, or kidney disease. Tell your doctor if you are on dialysis.
  • This medicine lowers the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.
  • Make sure your doctor knows if you are being treated for bee or wasp stings, or if you will soon be having any surgery.
  • This medicine may make you dizzy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.
  • This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Changes in how much or how often you urinate.
  • Chest pain, fast or slow heartbeat.
  • Confusion, weakness, uneven heartbeat, shortness of breath, or numbness or tingling in your hands, feet, or lips.
  • Dry mouth, increased thirst, muscle cramps, nausea or vomiting.
  • Fever, chills, cough, sore throat, or body ache.
  • Light-headedness, fainting.
  • Loss of movement of one side or any part of the body.
  • Severe stomach pain.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Blurred vision or ringing in your ears.
  • Dizziness, tired feeling.
  • Headache.
  • Increased sweating.
  • Loss of interest in sex.
  • Mild skin rash or itching.
  • Muscle or joint pain, weight gain.
  • Runny or stuffy nose.
  • Warmth or redness in your face, neck, arms, or upper chest.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: September 18, 2013

         
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