Factor xiii human (Injection)

Introduction

Factor XIII Human (FAK-tor THIR-teen HUE-man)

Prevents bleeding in patients with congenital Factor XIII deficiency.

Brand Name(s)

Corifact

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not receive this medicine if you have had an allergic reaction to a coagulation factor or to any products made from human blood.

How to Use This Medicine

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
  • A nurse or other trained health professional will give you this medicine.
  • This medicine is usually given every 28 days (4 weeks), depending on your recent blood test results.
  • This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding.
  • This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you or your child have a rash; itching or hives; dizziness; shortness of breath; trouble with breathing; chest tightness; swelling in your face, hands, tongue, or throat; or lightheadedness or faintness after you receive the medicine.
  • This medicine may increase your chance of having blood clotting problems. Tell your doctor right away if you or your child have a sudden or severe headache, problems with vision or speech, chest pain, shortness of breath, or numbness or weakness while you are receiving this medicine.
  • This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them. The risk of getting a virus from medicines made from human blood has been greatly reduced in recent years. This is the result of required testing of human donors for certain viruses, and testing during the making of these medicines. Although the risk is low, talk with your doctor if you have concerns.
  • Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash.
  • Chest pain, shortness of breath, or coughing up blood.
  • Deep, dark, purple bruise.
  • Fever or chills.
  • Lightheadedness, dizziness, or fainting.
  • Numbness or weakness in your arm or leg, or on one side of your body.
  • Pain in your lower leg (calf).
  • Redness, pain, swelling, or a lump under your skin where the needle is placed.
  • Sudden or severe headache, or problems with vision, speech, or walking.
  • Unexplained nosebleeds.

If you notice these less serious side effects, talk with your doctor:

  • Cough, runny or stuffy nose, sore throat, and body aches.
  • Diarrhea, nausea, vomiting, or stomach pain.
  • Headache.
  • Mild skin rash.
  • Muscle or joint pain.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: June 18, 2013

         
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