Erythromycin Lactobionate (e-rith-roe-MYE-sin lak-toe-BYE-oh-nate)
This medicine is a macrolide antibiotic used to treat bacterial infections. Also used to prevent heart infection and rheumatic fever in patients who have had an allergic reaction to penicillin or sulfa drugs.
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
Do not receive this medicine if you have had an allergic reaction to erythromycin. Do not receive this medicine if you are also using astemizole or terfenadine.
How to Use This Medicine
- Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
- A nurse or other trained health professional will give you this medicine.
- Your doctor may give you a few doses of this medicine until your condition improves and then switch you to an oral medicine that works the same way.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are using alfentanil (Alfenta®), bromocriptine (Parlodel®), carbamazepine (Tegretol®), cyclosporine (Gengraf®, Neoral®, Sandimmune®), digoxin (Lanoxin®), hexobarbital (Citopan®), lovastatin (Altocor®, Mevacor®), phenytoin (Dilantin®), theophylline (Theo-Dur®), valproate (Depakote®), or a blood thinner (such as warfarin, Coumadin®).
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or myasthenia gravis (severe muscle weakness).
- Tell your doctor right away if you have dark urine or pale stools, yellow skin or eyes, nausea and vomiting, or upper stomach pain. These could be symptoms of a serious liver problem.
- If you have severe diarrhea, ask your doctor before taking any medicine to stop the diarrhea.Diarrhea may occur 2 months or more after you stop using this medicine.
- Contact your doctor right away if you have any changes to your heart rhythm. You might feel dizzy or faint, or you might have a fast, pounding, or uneven heartbeat. Make sure your doctor knows if you or anyone in your family has ever had a heart rhythm problem such as QT prolongation.
- Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.
- If your symptoms do not improve or if they get worse, call your doctor.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, or red skin rash
- Dark-colored urine or pale stools
- Diarrhea that may contain blood
- Fast, pounding, or uneven heartbeat
- Hearing loss
- Nausea, vomiting, loss of appetite, or pain in your upper stomach
- Severe muscle weakness
- Yellowing of your skin or the whites of your eyes
If you notice these less serious side effects, talk with your doctor:
- Mild diarrhea
- Mild skin rash
- Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last Reviewed on 06/12/2013
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This page was last updated: June 18, 2013