Dyphylline (By mouth)


Dyphylline (DYE-fi-lin)

Treats asthma attacks and other lung problems such as emphysema and chronic bronchitis. This medicine is a bronchodilator.

Brand Name(s)

Lufyllin, Lufyllin-400

When This Medicine Should Not Be Used

How to Use This Medicine

Liquid, Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using ephedrine or probenecid (Benemid®). Tell your doctor if you are also using other medicines for breathing problems such as theophylline (Theolair®).
  • There are many medicines that can interact with this medicine. Make sure your doctor knows about all other medicines you are using.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding.
  • Make sure your doctor knows if you have high blood pressure, heart disease, kidney disease, an overactive thyroid, or stomach ulcers.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blood in your urine.
  • Bloody vomit.
  • Fast, uneven, or pounding heartbeat.
  • Increase in how much or how often you urinate.
  • Lightheadedness or fainting.
  • Rapid breathing.
  • Severe vomiting, agitation, extreme thirst, seizures.
  • Warmth or redness in your face, neck, arms, or upper chest.

If you notice these less serious side effects, talk with your doctor:

  • Feeling irritable, restless or agitated.
  • Headache or trouble sleeping.
  • Mild nausea, vomiting, diarrhea, or stomach pain.
  • Muscle twitching.
  • Pale, clammy skin.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 12/4/2015

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch)

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.