Diphenoxylate/atropine (By mouth)

Introduction

Atropine Sulfate (AT-roe-peen SUL-fate), Diphenoxylate Hydrochloride (dye-fen-OX-i-late hye-droe-KLOR-ide)

Treats diarrhea.

Brand Name(s)

Lonox, Lomotil, Lomocot

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you ever had an allergic reaction to atropine or diphenoxylate.

How to Use This Medicine

Liquid, Tablet

  • Your doctor will tell you how much to take and how often.
  • Measure the oral liquid medicine with a marked measuring spoon or medicine cup.
  • Drink plenty of caffeine-free, clear liquids such as ginger ale, tea, water, gelatin, or broth during the first 24 hours.

If a dose is missed:

  • Take the missed dose as soon as possible.
  • Skip the missed dose if it is almost time for your next regular dose.
  • You should not use two doses at the same time.

How to Store and Dispose of This Medicine

  • Store at room temperature, away from heat, moisture, and direct light. Do not freeze the oral liquid.
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are taking any drugs that could make you sleepy such as antidepressants, strong pain killers, cold and allergy medicine, or tranquilizers.
  • Tell your doctor if you are also taking an MAO inhibitor such as Marplan®, Parnate®, Nardil®, or Eldepryl®.

Warnings While Using This Medicine

  • Talk with your doctor before taking if you are pregnant, breastfeeding, or have liver or kidney disease, colitis, or other medical problems.
  • This medicine may cause drowsiness. Be careful if you drive a car or use machinery.
  • You should not use this medicine more often or in larger doses than your doctor ordered.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Seizures
  • Severe constipation with bloating
  • Irregular or fast heartbeat
  • Trouble breathing
  • Decreased or no urine for more than 8 hours

If you notice these less serious side effects, talk with your doctor:

  • Drowsiness, dizziness, or restlessness
  • Dry mouth
  • Blurred vision
  • Headache
  • Trouble urinating

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch)

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

This page was last updated: June 18, 2013

         
Average rating (0)