Dexlansoprazole (By mouth)
Treats erosive esophagitis, heartburn, gastroesophageal reflux disease (GERD), and other conditions caused by too much stomach acid. This medicine is a proton pump inhibitor (PPI).
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
Do not use this medicine if you have had an allergic reaction to dexlansoprazole.
How to Use This Medicine
Delayed Release Capsule
- Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- Delayed-release capsule: Swallow the capsule whole. Open the capsule and pour the medicine into a tablespoon of applesauce, if you cannot swallow it whole. Swallow the mixture right away. Do not chew it. Do not store the mixed medicine for later use.
- This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are using ampicillin (Principen®, Unasyn®), digoxin (Lanoxin®), ketoconazole (Nizoral®), methotrexate (Rheumatrex®, Trexall®), tacrolimus (Prograf®), an iron supplement, or a blood thinner (such as warfarin, Coumadin®, Jantoven®).
- Do not use atazanavir (Reyataz®) while you are taking this medicine.
- Make sure your doctor knows if you are also using a diuretic (water pill, such as furosemide, hydrochlorothiazide (HCTZ), indapamide, metolazone, torsemide, Demadex®, Lasix®, or Zaroxolyn®).
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have liver disease, osteoporosis, or a history of low magnesium levels in your blood.
- Rarely, this medicine may cause hypomagnesemia (low magnesium in the blood). This is more likely to occur if you take this medicine longer than 1 year, or if you take it with digoxin or certain diuretics (water pills). Tell your doctor right away if you have seizures, dizziness, a fast or pounding heartbeat, or muscle spasms.
- You may be at risk for Clostridium difficile colitis (also called C diff) if you take this medicine. C diff is inflammation in your large intestine that causes diarrhea. You have a higher risk of this condition if you are also using an antibiotic, are elderly, or have other chronic conditions.If you have severe diarrhea, ask your doctor before taking any medicine to stop the diarrhea.
- This medicine may increase your risk of broken bones in the hip, wrist, or spine. This is more likely if you are older than 50, if you take this medicine more than once a day, or if you use it for 1 year or longer.
- Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Fast, pounding, or uneven heartbeat
- Muscle spasms, cramps
- Severe diarrhea that does not go away, stomach pain, and fever
If you notice these less serious side effects, talk with your doctor:
- Mild diarrhea, gas
- Nausea, vomiting
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last Reviewed on 06/12/2013
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This page was last updated: June 18, 2013