Dalfampridine (By mouth)
Helps improve walking in patients with multiple sclerosis. This medicine is a potassium channel blocker.
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
Do not use this medicine if you have had an allergic reaction to dalfampridine or 4-aminopyridine, or if you have moderate or severe kidney disease or a history of seizures.
How to Use This Medicine
Long Acting Tablet
- Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- Wait about 12 hours between each dose. This medicine works best if you take it at evenly spaced times.
- Swallow the extended-release tablet whole. Do not crush, break, or chew it.
- This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one.
If a dose is missed:
- If you miss a dose or forget to take your medicine, skip the missed dose. Take your next regular dose at the next regular time.
- Do not take extra medicine to make up for the missed dose. Never take more than 2 tablets in a 24-hour period.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Do not take dalfampridine together with another aminopyridine medicine (such as compounded 4-AP or fampridine). Your risk for serious side effects increases if you take these medicines together.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease.
- Dalfampridine may cause seizures, even if you have not had a seizure before. Stop using this medicine and call your doctor right away if you have a seizure.
- This medicine may cause a urinary tract infection. Check with your doctor right away if you have pain when you urinate, bloody or cloudy urine, trouble urinating, frequent urge to urinate, or lower back or side pain.
- Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Bloody or cloudy urine
- Change in how much or how often you urinate
- Pain when you urinate or trouble urinating
If you notice these less serious side effects, talk with your doctor:
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last Reviewed on 06/12/2013
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This page was last updated: June 18, 2013