Dalfampridine (By mouth)

Introduction

Dalfampridine (dal-FAM-pri-deen)

Helps improve walking in patients with multiple sclerosis. This medicine is a potassium channel blocker.

Brand Name(s)

Ampyra

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

Do not use this medicine if you have had an allergic reaction to dalfampridine or 4-aminopyridine, or if you have moderate or severe kidney disease or a history of seizures.

How to Use This Medicine

Long Acting Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
  • Wait about 12 hours between each dose. This medicine works best if you take it at evenly spaced times.
  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.
  • This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one.

If a dose is missed:

  • If you miss a dose or forget to take your medicine, skip the missed dose. Take your next regular dose at the next regular time.
  • Do not take extra medicine to make up for the missed dose. Never take more than 2 tablets in a 24-hour period.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not take dalfampridine together with another aminopyridine medicine (such as compounded 4-AP or fampridine). Your risk for serious side effects increases if you take these medicines together.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease.
  • Dalfampridine may cause seizures, even if you have not had a seizure before. Stop using this medicine and call your doctor right away if you have a seizure.
  • This medicine may cause a urinary tract infection. Check with your doctor right away if you have pain when you urinate, bloody or cloudy urine, trouble urinating, frequent urge to urinate, or lower back or side pain.
  • Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Bloody or cloudy urine
  • Change in how much or how often you urinate
  • Pain when you urinate or trouble urinating
  • Seizures

If you notice these less serious side effects, talk with your doctor:

  • Nausea
  • Trouble sleeping

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch)

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

This page was last updated: June 18, 2013

         
Average rating (0)