Coagulation factor viia (Injection)

Introduction

Coagulation Factor VIIa (koh-a-gyoo-LAY-shun FAK-tor SEV-en A)

Treats and prevents bleeding episodes in people who have hemophilia A or B with inhibitors to Factor VIII or Factor IX. Also treats and prevents bleeding in patients with acquired hemophilia or congenital factor VII deficiency.

Brand Name(s)

Novoseven, NovoSeven RT

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to coagulation factor (recombinant), or to mouse, hamster, or bovine proteins (found in drugs such as abciximab, darbepoetin alfa, infliximab, Aranesp®, Remicade®, Reopro®, or Rituxan®).

How to Use This Medicine

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
  • A nurse or other trained health professional will give you this medicine.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using other coagulation factors or medicines that affect the blood such as aminocaproic acid (Amicar®) or tranexamic acid (Cyklokapron®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have a history of kidney disease, liver disease, heart disease, or blood clots known as disseminated intravascular coagulation (DIC). Tell your doctor if you have bleeding problems, any arterial diseases (such as blocked or hardened arteries), an infection, or any injury or untreated wounds.
  • This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you or your child have a rash; itching or hives; dizziness; shortness of breath; trouble with breathing; chest tightness; swelling in your face, hands, tongue, or throat; or lightheadedness or faintness after you receive the medicine.
  • This medicine may increase your chance of having blood clotting problems. Tell your doctor right away if you or your child have a sudden or severe headache, problems with vision or speech, chest pain, shortness of breath, or numbness or weakness while you are receiving this medicine.
  • Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
  • If your symptoms do not improve or if they get worse, call your doctor.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, shortness of breath, or coughing up blood.
  • Decrease in how much or how often you urinate.
  • Fast, slow, or uneven heartbeat.
  • Fever or chills.
  • Lightheadedness, dizziness, or fainting.
  • Numbness or weakness in your arm or leg, or on one side of your body.
  • Pain in your lower leg (calf).
  • Red or dark-brown urine, or black stool.
  • Redness, pain, or swelling where the IV is given.
  • Sudden or severe headache, problems with vision, speech, or walking.
  • Swelling in your hands, ankles, or feet.
  • Unusual bleeding, bruising, or weakness.

If you notice these less serious side effects, talk with your doctor:

  • Joint pain or swelling.
  • Nausea or vomiting.
  • Skin rash.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: June 18, 2013

         
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