Benazepril/hydrochlorothiazide (By mouth)
Benazepril Hydrochloride (ben-AZ-e-pril hye-droe-KLOR-ide), Hydrochlorothiazide (hye-droe-klor-oh-THYE-a-zide)
Treats high blood pressure. This medicine contains an ACE inhibitor and a diuretic (water pill).
When This Medicine Should Not Be Used
How to Use This Medicine
- Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
- Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Do not use this medicine together with aliskiren if you have diabetes.
- Some foods and medicines can affect how benazepril/hydrochlorothiazide works. Tell your doctor if you are using any of the following:
- Aliskiren, biperiden, cholestyramine, colestipol, cyclophosphamide, cyclosporine, digoxin, lithium, methotrexate
- Another blood pressure medicine, including an angiotensin receptor blocker (ARB)
- Insulin or other diabetes medicine
- NSAID pain or arthritis medicine (such as aspirin, celecoxib, diclofenac, ibuprofen, naproxen)
- Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.
- Alcohol, narcotic pain medicine, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine.
Warnings While Using This Medicine
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding, or if you have kidney problems, liver disease, congestive heart failure, diabetes, gout, heart disease, high cholesterol, lupus or a similar disorder, trouble urinating, or a history of asthma or allergies.
- This medicine may cause the following problems:
- Severe swelling, including intestinal angioedema
- Serious liver problems
- Kidney problems
- This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you are lightheaded or dizzy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
- Do not stop using the medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.
- Tell any doctor or dentist who treats you that you are using this medicine.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, or red skin rash
- Change in how much or how often you urinate
- Confusion, weakness, trouble breathing, numbness in your hands, feet, or lips
- Confusion, weakness, and muscle twitching
- Dry mouth, increased thirst, muscle cramps, nausea or vomiting
- Fast or uneven heartbeat
- Lightheadedness, dizziness, or fainting
- Severe stomach pain
- Trouble seeing, eye pain
If you notice these less serious side effects, talk with your doctor:
- Dry cough
- Unusual tiredness or weakness
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last reviewed on 7/4/2015
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