Azelastine/fluticasone (Into the nose)
Azelastine Hydrochloride (ay-ze-LAS-teen hye-droe-KLOR-ide), Fluticasone Propionate (floo-TIK-a-sone PROE-pee-oh-nate)
Treats symptoms of hay fever (allergic rhinitis). This medicine contains an antihistamine and a steroid.
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
Do not use this medicine if you have had an allergic reaction to azelastine or fluticasone.
How to Use This Medicine
- Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.
- This medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.
- You will need to prime the nasal spray before you use it for the first time. To do this, pump the bottle until some of the medicine sprays out. Now it is ready to use. Prime the spray if you have not used it for 14 days or more. Shake the medicine well before each use.
- Before using the medicine, gently blow your nose to clear the nostrils.
- After using the nasal spray, wipe the tip of the bottle with a clean tissue and put the cap back on.
- You may need to use this medicine for a few days before you start to feel better.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- Keep the bottle tightly closed when not using it. Store at room temperature, away from heat and direct light.Do not store in the freezer or refrigerator.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.Throw this medicine away after you use 120 sprays.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you also use fluconazole (Diflucan®), itraconazole (Sporanox®), ketoconazole (Nizoral®), or ritonavir (Kaletra®, Norvir®).
- Tell your doctor if you are using any medicines that make you sleepy. These include sleeping pills, cold and allergy medicine, narcotic pain relievers, and sedatives.Also tell your doctor if you drink alcohol.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding or if you have adrenal problems, asthma, glaucoma, cataracts, tuberculosis, an eye infection caused by herpes, or any type of infection (including a cold or the flu).
- Make sure your doctor knows if you have had recent nose sores or ulcers, surgery, or injury. You may need to stop using the medicine to allow your nose to heal.
- This medicine may cause nasal side effects. Check with your doctor right away if you have bloody mucus, sores inside the nose, unexplained nosebleeds, or a whistling sound when you breathe.
- This medicine may weaken your immune system and make it easier for you to get infections. Call your doctor if you have any signs of infection, such as fever, chills, cough, or sore throat. Tell your doctor if you develop white patches or sores in your mouth. Tell your doctor right away if you think you have been exposed to measles or chickenpox.
- This medicine may make you dizzy or drowsy. Do not drive, use machines, or do anything else that could be dangerous until you know how this medicine affects you.
- Check with your doctor immediately if blurred vision, difficulty reading, or any other change in vision occurs during or after treatment. Your doctor may want you to have your eyes checked by an eye doctor.
- This medicine may slow down a child's growth. Talk with your doctor if you think your child is not growing properly while using this medicine.
- Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Burning, redness, swelling, or irritation around or inside your nose
- Eye pain or changes with vision
- Fever, chills, cough, runny nose, sore throat, and body aches
- Heavy nosebleeds
- Sores or white patches inside the nose or mouth
- Unusual tiredness or weakness, diarrhea, nausea, or vomiting
If you notice these less serious side effects, talk with your doctor:
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last Reviewed on 06/12/2013
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This page was last updated: September 18, 2013