Alprostadil (Intravenous)


Alprostadil (al-PROS-ta-dil)

Treats infants who were born with certain heart, lung, and blood vessel problems. May help to increase the amount of oxygen-rich blood that is pumped from the heart to the body, until other treatments can be done.

Brand Name(s)

Prostin VR Pediatric

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

Your baby should not be given this medicine if he has had an allergic reaction to alprostadil.

How to Use This Medicine


  • A nurse or other trained health professional will give you this medicine.This medicine is given through a needle or a catheter placed in a vein. It may also be given through a catheter in your baby's umbilical cord.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine

  • Make sure caregivers know if your baby has problems with breathing, digestion, or bleeding.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast or slow heartbeat
  • Trouble breathing
  • Unusual bleeding, bruising, or weakness
  • Seizures, fainting, or becoming limp
  • Redness, swelling, or leaking from the IV site

If you notice these less serious side effects, talk with your doctor:

  • Joint swelling, or a decrease in movement of the arms or legs
  • Irritability
  • Diarrhea, swollen belly, vomiting, or other digestion problems
  • Fever, flushing (unusual warmth or redness of the skin), or problems keeping a warm body temperature

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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This page was last updated: June 18, 2013

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