Abobotulinumtoxina (Injection)


AbobotulinumtoxinA (ab-oh-bot-ue-LYE-num-tox-in-ay)

Treats pain, and improves the appearance of wrinkles on the face.

Brand Name(s)


When This Medicine Should Not Be Used

How to Use This Medicine


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
  • A nurse or other health provider will give you this medicine.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how abotulinumtoxinA works. Tell your doctor if you are taking any of the following:
    • Atropine
    • Hyoscyamine
    • Infection medicine, such as amikacin, gentamicin, streptomycin

Warnings While Using This Medicine

  • Tell your doctor if you are pregnant or breastfeeding, or if you have breathing problems (such as asthma or emphysema), a droopy eyelid, or skin problems (such as thick or oily skin). Tell your doctor if you have nerve or muscle problems (such as ALS [Lou Gehrig disease], Lambert-Eaton syndrome, or myasthenia gravis), or trouble with swallowing.
  • Tell your doctor if you have a scheduled surgery, you had surgery on your face, or you have received botulinum toxin for any reason in the past several months.
  • This medicine may make your muscles weak and cause vision problems. Do not drive or do anything else that could be dangerous if you feel weak or are not able to see well.
  • This medicine contains products from donated human blood, so it may contain viruses, although the risk is low. Human donors and blood are always tested for viruses to keep the risk low. Talk with your doctor about this risk if you are concerned.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash
  • Blurred or double vision
  • Fever, chills, cough, stuffy or runny nose, sore throat, and body aches
  • Loss of bladder control
  • Neck pain
  • Trouble with breathing, speaking, or swallowing
  • Unusual weakness in other muscles (not where the shot was given)

If you notice these less serious side effects, talk with your doctor:

  • Change or loss of voice
  • Drooping or swelling of your eyelids, or dry eyes
  • Dry mouth or nausea
  • Headache or tiredness
  • Redness, pain, tenderness, bruising, swelling, or weakness where the shot was given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 12/4/2015

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