Abciximab (Injection)

Introduction

Abciximab (ab-SIX-i-mab)

Prevents blood clots from forming during a procedure to open blocked blood vessels.

Brand Name(s)

Reopro

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to abciximab or murine proteins, or under certain conditions that may affect blood clotting. These conditions may include a personal or family history of bleeding problems, internal bleeding within the past 6 weeks (including bleeding ulcers or blood in your urine), a history of stroke, using a blood thinner such as warfarin (Coumadin®) within the past week, major surgery or injury within the last 6 weeks, cancer, very high blood pressure, or vasculitis.

How to Use This Medicine

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
  • A nurse or other trained health professional will give you this medicine.
  • You may also receive other blood thinners, such as aspirin and heparin, which will work together to help keep you from getting blood clots.
  • You will get a dose of the medicine before your procedure and will continue to receive the medicine for about 12 hours afterwards.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using dipyridamole (Persantine®, Aggrenox®), ticlopidine (Ticlid®), a blood thinner such as warfarin (Coumadin®), thrombolytic medicine such as alteplase (Activase®) and streptokinase (Streptase®), or pain or arthritis medicine (such as aspirin, diclofenac, etodolac, ibuprofen, indomethacin, Advil®, Aleve®, Daypro®, Dolobid®, Feldene®, Indocin®, Motrin®, Orudis®, Relafen®, or Voltaren®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding.
  • This medicine may cause you to bleed more easily. This is more likely to happen within the first several hours, but this effect may last up to 3 days. Be careful to not cut or bruise yourself.
  • You will probably need to stay in bed for several hours after you stop getting this medicine.
  • Tell your doctor if you have received abciximab before.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
  • Blood in the urine or bloody or black, tarry stools
  • Unusual bleeding or bruising, especially where the IV needle or catheter was placed
  • Vomiting blood or material that looks like coffee grounds

If you notice these less serious side effects, talk with your doctor:

  • Back pain
  • Lightheadedness or fainting

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch)

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

This page was last updated: June 18, 2013

         
Average rating (0)