Possible Interactions with: Vitamin B6 (Pyridoxine)

Interactions

If you are being treated with any of the following medications, you should not use vitamin B6 supplements without first talking to your health care provider.

Drugs that reduce levels of B6 in the body -- If you take any of these medications, be sure to get enough B6 in your diet:

  • Cycloserine (Seromycin), used to treat tuberculosis
  • Hydralazine (Apresoline), used to treat high blood pressure
  • Isoniazid, used to treat tuberculosis
  • Penicillamine, used to treat rheumatoid arthritis
  • Theophylline (TheoDur), used to treat asthma

Antibiotics, Tetracycline -- All B complex vitamins, including vitamin B6, interfere with the absorption and effectiveness of antibiotic tetracycline. You should take tetracyclien at different times from vitamin B6 and other B vitamins.

Antidepressant Medications -- Taking vitamin B6 supplements may improve the effectiveness of certain tricyclic antidepressants such as nortriptyline (Pamelor), especially in elderly people. Other tricyclic antidepressants include amitriptyline (Elavil), desipramine (Norpramin), and imipramine (Tofranil).

On the other hand, antidepressants called monoamine oxidase inhibitors (MAOIs) may reduce blood levels of vitamin B6. Examples of MAOIs include phenelzine (Nardil) and tranylcypromine (Parnate).

Chemotherapy drugs -- Vitamin B6 may reduce certain side effects of 5-fluorouracil and doxorubicin, medications used to treat cancer, without reducing the effectiveness of the chemotherapy. Talk to your doctor before taking any supplement if you are undergoing chemotherapy.

Erythropoietin (EPO) -- Erythropoietin therapy, used to treat severe anemia, may decrease vitamin B6 levels in red blood cells and may require B6 supplementation.

Levodopa (L-dopa)-- Vitamin B6 reduces the effectiveness of levodopa, a medication used to treat Parkinson's disease. However, your doctor may be able to determine a dose of B6 that can help reduce side effects of levodopa without interfering with the drug's action. Taking vitamin B6 along with levodopa should be done only under the strict guidance of a physician.

Phenytoin (Dilantin) -- Vitamin B6 reduces the effectiveness of phenytoin, a medication used to treat seizures.

Drug Interactions

Antipsychotic MedicationsBirth Control MedicationsHydralazineLevodopaPhenytoin-containing MedicationsTetracyclineTheophylline-containing MedicationsTricyclic Antidepressants

Alternative Names

Pyridoxine; Vitamin B6 (Pyridoxine)

Version Info

  • Last Reviewed on 09/04/2007
  • Steven D. Ehrlich, N.M.D., private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch)

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

This page was last updated: May 31, 2013

         
Average rating (0)