Antidiabetic medications - sulfonylureas

Medications

Sulfonylureas antidiabetic medication includes:

  • Acetohexamide (Dymelor)
  • Chlorpropamide (Diabinese)
  • Glipizide (Glucotrol and Glucotrol XL)
  • Glyburide (Diaßeta, Glynase PresTab, and Micronase)
  • Tolazamide (Tolinase)
  • Tolbutamide (Orinase and Tol-Tab)

Depletions

Coenzyme Q10

Coenzyme Q10 is an antioxidant. It is rare to be so deficient in CoQ10 that you have symptoms, which include:

  • Muscle weakness and pain
  • Fatigue
  • Gum disease
  • Weakened immune system

However, some research shows that low levels of CoQ10 over an extended period of time may be linked to heart disease and high blood pressure.

Editorial Note

The information presented here covers some of the nutrients that may be affected when you take certain medications. If you have the signs and symptoms listed, it does not always mean you have low levels of these nutrients. Many things affect the level of nutrients, including your:

  • Medical history
  • Diet
  • Lifestyle

As well as how long you have been taking the medication. Please talk with your health care provider. They can best address your health care needs and determine whether you are at risk for low levels of any nutrients.

Supporting Research

Bonakdar RA, Guarneri E. Coenzyme Q10. Am Fam Physician. 2005;72(6):1065-70.

Littarru GP, Tiano L. Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Mol Biotechnol. 2007;37(1):31-7.

Pelton R, LaValle J, Hawkins EB, et al. Drug Induced Nutrient Depletion Handbook. Hudson, OH:LexiComp, Inc.;2001:409.

Pepe S, Marasco SF, Haas SJ, Sheeran FL, Krum H, Rosenfeldt FL. Coenzyme Q10 in cardiovascular disease. Mitochondrion. 2007;7 Suppl:S154-67.

Powers HJ. Riboflavin (vitamin B-2) and health. Am J Clin Nutr. 2003;77(6):1352-60.

Quinzii CM, Hirano M, DiMauro S. CoQ10 deficiency diseases in adults. Mitochondrion. 2007;7 Suppl:S122-6.

Young AJ, Johnson S, Steffens DC, Doraiswamy PM. Coenzyme Q10: a review of its promise as a neuroprotectant. CNS Spectr. 2007;12(1):62-8.

Version Info

  • Last reviewed on 8/27/2014
  • Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed HealthCare Network. Also reviewed by the A.D.A.M. Editorial team.

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