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Acetohydroxamic Acid


Pronunciation

 (a SEE toe hye droks am ik AS id)


U.S. Brand Names

 Lithostat®


Synonyms

 AHA


Generic Available

 No


Canadian Brand Names

 Lithostat®


Use

 Adjunctive therapy in chronic urea-splitting urinary infection


Pregnancy Risk Factor

 X


Lactation

 Excretion in breast milk unknown/not recommended


Ethanol/Nutrition/Herb Interactions

 Ethanol: Avoid ethanol (may increase incidence of rash)


Dosage

 Oral:

Children: Initial: 10 mg/kg/day

Adults: 250 mg 3-4 times/day for a total daily dose of 10-15 mg/kg/day


Dietary Considerations

 Should be taken 1 hour before or 2 hours after meals.


Patient Education

 Take as directed, preferably 1 hour before or 2 hours after meals. Avoid alcohol (rash may occur). You may experience increased anxiety, malaise, or headache; use caution when driving or engaging in hazardous tasks until response is known. Small, frequent meals may reduce incidence of nausea. Report persistent acute headache, nausea, or vomiting. Pregnancy/breast-feeding precautions: Inform prescriber if you are pregnant. Do not get pregnant or have sex unless using appropriate contraception while on this medication. This drug may cause severe fetal defects. Consult prescriber if breast-feeding.


Dental Health: Effects on Dental Treatment

 No significant effects or complications reported


Dental Health: Vasoconstrictor/Local Anesthetic Precautions

 No information available to require special precautions


Mental Health: Effects on Mental Status

 None reported


Mental Health: Effects on Psychiatric Treatment

 None reported


Dosage Forms

 Tablet: 250 mg


International Brand Names

 Lithostat® (CA); Uronefrex® (BE, ES, LU)


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