Factor intrínseco

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Definición

Es una proteína que le ayuda a los intestinos a absorber la vitamina B12 y lo producen células en el revestimiento del estómago. 

Nombres alternativos

Información

El factor intrínseco es una importante proteína que le ayuda al cuerpo a absorber la vitamina B12, necesaria para que los glóbulos rojos se formen y crezcan.

Algunas personas no producen suficiente factor intrínseco o tienen una enfermedad que lo destruye. Si su cuerpo no produce suficiente factor intrínseco, se puede desarrollar un tipo de deficiencia de vitamina B12, llamada anemia perniciosa.

La extirpación quirúrgica del estómago y algunas otras afecciones también pueden provocar que se deje de producir factor intrínseco.

Referencias

Antony AC. Megaloblastic anemias. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 167.

Antony AC. Megaloblastic anemia. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 39.

Version Info

  • Last Reviewed on 02/08/2012
  • Todd Gersten, MD, Hematology/Oncology, Palm Beach Cancer Institute, West Palm Beach, FL. Review provided by VeriMed Healthcare Network. Also reviewed by Linda J. Vorvick, MD, Medical Director and Director of Didactic Curriculum, MEDEX Northwest Division of Physician Assistant Studies, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington; David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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This page was last updated: May 31, 2013

         
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