Toggle: English / Spanish
Agitation is an unpleasant state of extreme arousal. An agitated person may feel stirred up, excited, tense, confused, or irritable.
Agitation can come on suddenly or over time. It can last for a few minutes, for weeks, or even months. Pain, stress, and fever can all increase agitation.
Agitation by itself may not be a sign of a health problem. But if other symptoms occur, it can be a sign of disease.
Agitation with a change in alertness (altered consciousness) can be a sign of delirium. Delirium has a medical cause and should be checked by a health care provider right away.
There are many causes of agitation. Some of them are:
- Alcohol intoxication or withdrawal
- Allergic reaction
- Caffeine intoxication
- Certain forms of heart, lung, liver, or kidney disease
- Intoxication or withdrawal from drugs of abuse (such as cocaine, marijuana, hallucinogens, PCP, or opiates)
- Hospitalization (older adults often have delirium while in the hospital)
Overactive thyroid gland (hyperthyroidism)
- Infection (especially in elderly people)
- Nicotine withdrawal
- Poisoning (for example, carbon monoxide poisoning)
- Some medicines, including theophylline, amphetamines, and steroids
- Vitamin B6 deficiency
Agitation can occur with brain and mental health disorders, such as:
The most important way to deal with agitation is to find and treat the cause. Agitation may lead to an increased risk of suicide and other forms of violence.
After treating the cause, the following measures can reduce agitation:
A calm environment
Enough lighting during the day and darkness at night
Medicines such as benzodiazepines, and in some cases, antipsychotics
Plenty of sleep
DO NOT physically hold back an agitated person, if possible. This usually makes the problem worse. Use restraints only if the person is at risk of harming themselves or others, and there is no other way to control the behavior.
When to Contact a Medical Professional
Contact your provider for agitation that:
- Lasts a long time
- Is very severe
- Occurs with thoughts or actions of hurting yourself or others
- Occurs with other, unexplained symptoms
What to Expect at Your Office Visit
Your provider will take a medical history and do a physical examination. To better understand your agitation, your provider may ask you specific things about your agitation.
Tests may include:
- Blood tests (such as a blood count, infection screening, thyroid tests, or vitamin levels)
- or scan
- Lumbar puncture (spinal tap)
- Urine tests (for infection screening, drug screening)
- (temperature, , breathing rate, blood pressure)
American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Arlington, VA: American Psychiatric Publishing; 2013.
Bope ET, Kellerman RD. Psychiatric disorders. In: Bope ET, Kellerman RD, eds. Conn's Current Therapy 2016. Philadelphia, PA: Elsevier; 2016:section 15.
Inouye SK. Delirium or acute mental status change in the older patient. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 28.
Prager LM, Ivkovic A. Emergency psychiatry. In: Stern TA, Rosenbaum JF, Fava M, Wilens TE, Rosenbaum JF, eds. Massachusetts General Hospital Comprehensive Clinical Psychiatry. 2nd ed. Philadelphia, PA: Elsevier; 2016:chap 88.
Young JL, Rund DA. Mood disorders. In: Marx JA, Hockberger RS, Walls RM, et al, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 8th ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 111.
- Last reviewed on 2/21/2016
- Timothy Rogge, MD, Medical Director, Family Medical Psychiatry Center, Kirkland, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.