Diuretics - potassium-sparing diuretics
Osteoporosis (bone loss) is the primary disease associated with long-term calcium deficiency. It may be associated with bone pain and spinal deformity. Depleted levels can also cause muscle cramps, irregular heartbeat, and depression.Vitamin B9 (Folic Acid)
Low levels of folic acid have been linked to anemia, heart disease, depression, and birth defects. Symptoms may include fatigue, mouth sores, swollen tongue, and poor growth.
The information presented here covers some of the nutrients that may be affected when you take certain medications. If you have the signs and symptoms listed, it doesn't always mean you have low levels of these nutrients. Many things affect the level of nutrients, including your medical history, diet, and lifestyle, as well as how long you have been taking the medication. Please talk with your health care provider. He or she can best assess your health care needs and determine whether you are at risk for low levels of any nutrients.
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Morrow LE, Grimsley EW. Long-term diuretic therapy in hypertensive patients: effects on serum homocysteine, vitamin B6, vitamin B12, and red blood cell folate concentrations. South Med J. 1999;92:866-70.
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Pelton R, LaValle J, Hawkins EB, et al. Drug Induced Nutrient Depletion Handbook. Hudson, OH:LexiComp, Inc. 2001:442-443.
Sheweita SA, Khoshhal KI. Calcium metabolism and oxidative stress in bone fractures: role of antioxidants. Curr Drug Metab. 2007;8:519-25.
- Last reviewed on 9/21/2014
- Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed HealthCare Network. Also reviewed by the A.D.A.M. Editorial team.
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